Thursday, November 10, 2016

NSU Scientists Study Disease that Impacts Hundreds of Thousands of Gulf War Veterans

PRESS RELEASE - FOR IMMEDIATE RELEASE
Nova Southeastern University Scientists Study Disease that Impacts Hundreds of Thousands of Gulf War Veterans

Tuesday, October 25, 2016

New Study Links Chemical Alarms to Negative Brain Changes

(91outcomes.com) - Newly released study results suggest that 1991 Gulf War exposures that triggered chemical alarms damaged veterans' brain structure and function.

The study results, published this month in the peer-reviewed Journal of Occupational and Environmental Medicine, looked at 1991 Gulf War veterans' self-reports of hearing chemical alarms going off during the war.  Previous estimates have suggested chemical alarms sounded tens of thousands of times across the Gulf War theater of operations during the six-week war to oust Iraqi military occupying forces from Kuwait.

A pair of studies in 2012 by Dr.'s James Haley and James Tuite provided new evidence that supports that chemical plumes from destroyed Iraqi chemical warfare production and storage facilities drifted down over and exposed large numbers of Gulf War troops to low-levels of sarin, mustard, and other Iraqi chemical warfare agents.

Friday, October 21, 2016

CDMRP Publicizes New Resources, including Gulf War Illness "Landscape"

(91outcomes.com) - Two significant new publicly available resources have been developed and publicly released by the Gulf War Illness Research Program (GWIRP), part of the U.S. Department of Defense Congressionally Directed Medical Research Programs (CDMRP).  

The Gulf War Illness Landscape

The first new GWIRP public resource, just released today, is the GWIRP's "landscape" of Gulf War illness (GWI) research.  The GWIRP prepared this Landscape as an overview of what is currently known about topics consistent with the GWIRP's integrated, three-part, Congressionally-directed mission: identifying GWI treatments; improving the definition and diagnosis of GWI; and, understanding GWI's pathobiology and symptoms.

Wednesday, October 5, 2016

CDMRP-Funded Study Testing 9 Treatments for Gulf War Illness

(91outcomes.com) - A new study funded by the Congressionally Directed Medical Research Program (CDMRP) is testing nine different treatments in veterans with Gulf War Illness.

The study, Treating Gulf War Illness with Novel Anti-Inflammatories: A Screening of Botanical Microglia Modulators, is being led by Dr. Jarred Younger of the University of Alabama at Birmingham.  During the course of the study, investigators will test the treatment viability of each of the nine plant-based treatments -- three in each veteran participant.  

Friday, September 30, 2016

CDMRP-Funded Study Finds 3 Blood Biomarkers of Gulf War Illness, Advances Toward Treatments

(91outcomes.com) - A Minnesota researcher has identified three "readily measurable" biomarkers in the blood of 1991 Gulf War veterans suffering from Gulf War Illness that may help enhance the current case definition for the disease and aid in treatment trials.  

Supported by a U.S. Department of Defense (DoD) research grant, Dr. Ronald Bach of the Minneapolis VA Medical Center and his research team identified the biomarkers, which include specific changes in lymphocytes, monocytes, and C reactive protein.  Additionally, "Lymphocyte, monocyte, neutrophil, and platelet counts were higher in GWI subjects. Six serum proteins associated with inflammation were significantly different in GWI subjects."

CDMRP-Funded Study Finds 3 Blood Biomarkers of Gulf War Illness, Advances Toward Treatments

(91outcomes.com) - A Minnesota researcher has identified three "readily measurable" biomarkers in the blood of 1991 Gulf War veterans suffering from Gulf War Illness that may help enhance the current case definition for the disease and aid in treatment trials.  

Wednesday, September 28, 2016

VA Study Confirms Worse Sleep Quality, Higher Sleep Apnea Risk in Gulf War Illness


(91outcomes.com) - A new study by the U.S. Department of Veterans Affairs (VA) shows that veterans suffering from Gulf War Illness (GWI) have greater risk for obstructive sleep apnea than similar veterans without the debilitating condition.

The study, led by longstanding VA GWI researcher Dr. Linda Chao, also found that veterans with GWI had significantly greater severity of insomnia and worse sleep quality.

Interestingly, the study found a close correlation between insomnia and severity and GWI status.

CDMRP Study Confirms, Builds on Previous Findings that Gulf War Toxins Lead to Long-Term Brain Inflammation

(91outcomes.com) - A study funded by a federal medical research program aimed at developing treatments for Gulf War Illness has found new insight into possible treatment pathways for the debilitating condition that affects as many as one-third of the veterans of the 1991 Gulf War.

The study also confirmed previous findings of persistent neurological inflammation in a mouse model following Gulf War toxic exposures. 

Most notably, according to the study's findings, "the persistent neuroinflammation evident in our model presents a platform with which to identify novel biological pathways, correlating with emergent outcomes that may be amenable to therapeutic targeting. Furthermore, in this work we confirmed our previous findings that GW [Gulf War] agent exposure causes neuropathological changes....