Editor's note: Fibromyalgia is a presumptive condition for Gulf War veterans for VA service-connected disability claims. Many Gulf War Illness researchers believe that the chronic widespread pain suffered by many Gulf War Illness patients is medically distinct from Fibromyalgia. Nevertheless, the recommendations below regarding resistance muscle training.
SOURCE: Arthritis Research & Therapy, Sep. 17, 2015, written by Kim Jones.
Thursday, September 24, 2015
SOURCE: US News & World Report - HealthDay. Mary Elizabeth Dallas reporting. 9/23/2015.
By Mary Elizabeth Dallas, HealthDay Reporter
WEDNESDAY, Sept. 23, 2015 (HealthDay News) -- Unexplained chronic fatigue, muscle pain and problems with thinking are experienced by a quarter of Gulf War veterans, and new research suggests exposure to DNA-damaging chemicals may cause this condition, known as Gulf War Syndrome.
Previous studies have suggested that the symptoms stem from a malfunction of mitochondria, the site in cells where molecules that power the body are made. The mitochondria have their own DNA, separate from the cell's.
Increases in mitochondrial DNA damage the mitochondria's ability to produce energy, leaving the individual feeling slow and tired. And the new study found direct evidence of increased damage to this cell powerhouse among Gulf War vets.
Researchers analyzed blood samples to measure the amount of mitochondrial DNA and degree of damage to this DNA among veterans with Gulf War Illness (GWI).
The vets not only had more mitochondrial DNA, but also more mitochondrial DNA damage than otherwise healthy adults, the researchers found.
Study author Yang Chen, a doctoral researcher at Rutgers Biomedical and Health Sciences in New Jersey, presented the findings at a recent meeting of the American [Physiological] Association in Tampa, Fla.
"Future studies are necessary to confirm these findings and determine their association with mitochondrial function. Work in this area may guide new diagnostic testing and treatments for veterans suffering from GWI," the study's authors wrote.
Monday, September 14, 2015
SOURCE: American Physiological Society, Sep. 11, 2015, Written by Staff Editor.
For Veterans with Gulf War Illness, an Explanation for the Unexplainable SymptomsBy Staff Editor
Sep 11, 2015 - 10:34:25 AM
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The mitochondrion has its own DNA, separate from the cell's, that encodes the proteins needed to produce the molecules that power the body's processes. Damage to the mitochondrial DNA (mtDNA) directly affects the mitochondria's ability to function and produce energy. Increases in the amount of mtDNA have been associated with disease. In this study, researchers measured the mtDNA amount and degree of mtDNA damage in blood cells from blood samples from veterans with GWI.
Compared with healthy non-deployed controls, Gulf War veterans had more mtDNA content and greater mtDNA damage. According to the researchers, these findings further support that mitochondrial dysfunction may be involved in GWI. "Future studies are necessary to confirm these findings and determine their association with mitochondrial function. Work in this area may guide new diagnostic testing and treatments for veterans suffering from GWI," the researchers wrote.
Yang Chen, MS, doctoral researcher at Rutgers Biomedical and Health Sciences, will present "Mitochondrial DNA is damaged in military veterans with fatiguing conditions" as part of the symposium "Translational Bioenergetics" on Thursday, Sept. 10, at 5:05 PM EDT in the Harbour Island Ballroom of the Westin Tampa Harbour Island.
This work was conducted with funding from Veteran Affairs (VA) Clinical Science Research & Development Service awarded to Michael J. Falvo, PhD, at the War Related Illness and Injury Study Center at VA-New Jersey Health Care System in East Orange, N.J.
NOTE TO JOURNALISTS: To read the full abstract or to schedule an interview with a member of the research team, please contact the APS Communications Office at firstname.lastname@example.org or 301-634-7209. Find more research highlights in the APS Press Room.
About the American Physiological Society
Physiology is the study of how molecules, cells, tissues and organs function in health and disease. Established in 1887, the American Physiological Society (APS) was the first U.S. society in the biomedical sciences field. The Society represents more than 11,000 members and publishes 14 peer-reviewed journals with a worldwide readership.
Saturday, September 12, 2015
SOURCE: Stars and Stripes, Sep. 10, 2015