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Thursday, August 18, 2016

JOEM: Hearing Gulf War Chemical Alarms Associated with Cognitive Decline

SOURCE:  Journal of Environmental Medicine (JOEM), Post Author Corrections: August 10, 2016
doi: 10.1097/JOM.0000000000000851
Original Article: PDF Only
http://journals.lww.com/joem/toc/9000/00000


SOURCE:  PubMed:

http://www.ncbi.nlm.nih.gov/pubmed/27513172



ARCHIVED ABSTRACT:

 2016 Aug 10. [Epub ahead of print]

Associations Between the Self-Reported Frequency of Hearing Chemical Alarms in Theater and Visuospatial Function in Gulf War Veterans.

Abstract


OBJECTIVE: 

The aim of this study was to examine the relationship between the self-reported frequencies of hearing chemical alarms during deployment and visuospatial function in Gulf War (GW) veterans.

METHODS: 

The relationship between the self-reported frequency of hearing chemical alarms, neurobehavioral, and volumetric brain imaging data was examined with correlational, regression, and mediation analyses.

RESULTS: 

The self-reported frequency of hearing chemical alarms was inversely associated with and significantly predicted performance on a visuospatial task (ie, Block Design) over and above potentially confounding variables, including concurrent, correlated GW-related exposures. This effect was partially mediated by the relationship between hearing chemical alarms and lateral occipital cortex volume.

CONCLUSIONS: 

Exposure to substances that triggered chemical alarms during GW deployment likely had adverse effects on veterans' brain structure and function, warranting further investigation of whether these GW veterans are at an increased risk for dementia.

[PubMed - as supplied by publisher]

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