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Friday, May 20, 2016

New Study Finds Brain Function Differences in Gulf War Illness National Sample



SOURCE:   PubMed (published in Psychiatric Res.), April 30, 2016, by researchers Dr. CM Cooper, Richard W. Briggs, Robert Haley, et al.

http://www.ncbi.nlm.nih.gov/pubmed/27017423

ARCHIVED ABSTRACT:

 2016 Apr 30;250:33-41. doi: 10.1016/j.pscychresns.2016.03.004. Epub 2016 Mar 18.

Memory and functional brain differences in a national sample of U.S. veterans with Gulf War Illness.

Abstract

Roughly 26-32% of U. S. veterans who served in the 1991 Persian Gulf War report suffering from chronic health problems. Memory complaints are regularly reported by ill Gulf War veterans (GWV), but limited data verify their complaints. This study investigated episodic memory and brain function in a nationally representative sample of GWV, using a face-name memory task and functional magnetic resonance imaging during encoding. A syndrome classification system was used to subdivide ill GWV into the three major Gulf War Illness syndrome types, "impaired cognition" (GWV-1), "confusion ataxia" (GWV-2), and "central pain" (GWV-3). Memory and brain function of ill GWV were contrasted to deployed and nondeployed well GWV controls (GWV-C). Ill GWV exhibited impaired memory function relative to GWV-C but the patterns of functional brain differences varied. Brain activation differentiated the GWV-C from the ill GWV. The different syndrome types also differed from one another in several brain regions. Additionally, the current study was the first to observe differences in brain function between deployed and nondeployed GWV-C. These results provide (1) evidence of memory impairment in ill GWV and differentiate the syndrome types at a functional neurobiological level, and (2) the role of deployment in the war on brain function. 
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

KEYWORDS: 

Associative memory; Encoding; Gulf War Illness; fMRI
PMID:
 
27017423
 
[PubMed - in process]

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