The article below is an update on an ongoing Gulf War Illness treatment study that compares nasal irrigation with saline (NI-S) and nasal irrigation with xylitol (NI-X) in 1991 Gulf War veterans who are suffering from Gulf War Illness with fatigue, and chronic sinusitis, a commonly reported symptom in Gulf War Illness patients.
Outcomes measured in the study include: fatigue-specific and overall health-related quality of life; pro-inflammatory cellular and cytokine profiles; cost-effectiveness and participant satisfaction.
Read this May 2011 91outcomes article, "Promising New Treatment for GWI Sinusitis Funded for CDMRP Study," for more information about this study and the nasal irrigation with xylitol.
The study, based in Madison, Wis., is currently recruiting additional 1991 Gulf War veterans with Gulf War Illness who have fatigue and chronic sinusitis. Veterans need to live near enough to Madison to be able to easily travel to the study site for multiple visits.
For contact information and more about this study, see this ClinicalTrials.gov overview.
Contemp Clin Trials. 2015 Jan 24. pii: S1551-7144(15)00020-8. doi: 10.1016/j.cct.2015.01.008. [Epub ahead of print]
Effectiveness of Nasal Irrigation for Chronic Rhinosinusitis and Fatigue in Patients with Gulf War Illness: Protocol for a Randomized Controlled Trial.
Hayer SD1, Rabago DP2, Amaza IP1, Kille T3, Zgierska A1, Zakletskaia L1, Krahn D4, Obasi CN1, Molander RC4.
CLINICAL TRIAL REGISTRATION:
Clinical Trials.gov Identifier NCT01700725.
Copyright © 2015. Published by Elsevier Inc.
Gulf War Illness; chronic rhinosinusitis; fatigue; nasal irrigation; veterans; xylitol